Monoclonal Antibody Purification with Protein A IMCStips

Immunotherapy entails the treatment of disease by inducing, enhancing, or suppressing an immune response. Immunotherapy is used to treat many different diseases, most notably, cancer and autoimmune diseases. 

However, antibody drug development is a long process. Currently monoclonal antibody purification has issues including:

  • difficult to automate
  • time consuming
  • expensive

There are 60+ FDA approved therapeutic antibodies like:

  • Humira
  • Rituxan
  • Herceptin

and biopharmaceutical companies are continuing to develop more drugs for immunotherapy.



Protein A IMCStips solve many of the current issues with purifying monoclonal antibodies. IMCStips utilize a patented dispersive pipette extraction technology, which leverages turbulent mixing to increase contact time between resin and analyte. This results in:

  • increased binding
  • rapid extraction times
  • consistent results


IMCStips reduce the need for multiple pipetting and centrifugation steps in a typical antibody purification process. IMCStips are available on most automated liquid handling systems and IMCS offers high-throughput, optimized purification methods for Protein A, affinity purification.


Download Protein A Application Note